LAMARC 2.0: maximum likelihood and Bayesian estimation of population parameters
نویسنده
چکیده
UNLABELLED We present a Markov chain Monte Carlo coalescent genealogy sampler, LAMARC 2.0, which estimates population genetic parameters from genetic data. LAMARC can co-estimate subpopulation Theta = 4N(e)mu, immigration rates, subpopulation exponential growth rates and overall recombination rate, or a user-specified subset of these parameters. It can perform either maximum-likelihood or Bayesian analysis, and accomodates nucleotide sequence, SNP, microsatellite or elecrophoretic data, with resolved or unresolved haplotypes. It is available as portable source code and executables for all three major platforms. AVAILABILITY LAMARC 2.0 is freely available at http://evolution.gs.washington.edu/lamarc
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ورودعنوان ژورنال:
- Bioinformatics
دوره 22 6 شماره
صفحات -
تاریخ انتشار 2006